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Prescription Drug Index

ALLOPURINOL

This is a Generic Prescription Drug


Allopurinol

Pronounced: al-oh-pure-i-nole

Other Name(s): Zyloprim


Allopurinol is used in the treatment of many symptoms of gout including tophi (collection of uric acid crystals in the tissues especially around joints) joint destruction and uric acid stones. Gout is a form of arthritis characterized by increased blood levels of uric acid. Allopurinol works by reducing uric acid production in the body thus preventing crystals from forming.

Allopurinol is also used to manage the increased uric acid levels in the blood of people with certain cancers such as leukemia. It is also prescribed to manage some types of kidney stones.

ADULTS

Your doctor will tailor the dosage of Allopurinol individually to control the severity of symptoms and to bring the uric acid levels to normal or near normal.

Gout

The usual starting dose is 100 milligrams once daily. Your doctor may increase your dose by 100 milligrams per day at 1-week intervals until desired results are attained. The average dose is 200 to 300 milligrams per day for mild gout and 400 to 600 milligrams daily for moderate to severe gout. The most you should take in a day is 800 milligrams.

Recurrent Kidney Stones

The usual dose is 200 to 300 milligrams daily divided into smaller doses or taken as one dose.

Management of Uric Acid Levels in Certain Cancers

The usual dose is 600 to 800 milligrams daily for 2 to 3 days together with a high fluid intake.

CHILDREN

The usual recommended dose for children 6 to 10 years of age is 300 milligrams daily for the management of uric acid levels in certain types of cancer. Children under 6 years of age are generally given 150 milligrams daily.

*Notify your doctor should you experience a skin rash or any influenza-type symptoms (fever chills muscle aches and pains nausea or vomiting) that occur along with a rash or shortly after the rash. These symptoms may rarely indicate a severe hypersensitivity reaction where medical treatment is required.

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Note:

The content in this section is provided for informational purposes only. This information regarding the following Canadian drugs is not intended to replace or act as a substitute for information or advice provided by your physician. You should always consult a physician before beginning a new medication. Moreover, prescription drugs should only be obtained with a doctor's prescription.

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