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Prescription Drug Index

PLAQUENIL

This is a Brand Name Prescription Drug


Plaquenil

Pronounced: PLAK-en-ill

Generic name: Hydroxychloroquine sulfate


Plaquenil is prescribed for the prevention and treatment of certain forms of malaria. Plaquenil is also used to treat the symptoms of rheumatoid arthritis such as swelling inflammation stiffness and joint pain. It is also prescribed for lupus erythematosus a chronic inflammation of the connective tissue.

ADULTS

Restraint or Prevention of Malaria

The usual dose is 400 milligrams taken once every 7 days on exactly the same day of each week. If circumstances permit preventive therapy should begin 2 weeks prior to exposure. If this is not possible your doctor will have you take a starting dose of 800 milligrams which may be divided into 2 doses taken 6 hours apart. You should continue this suppressive therapy for 8 weeks after leaving the area where malaria occurs.

Acute Attack of Malaria

The usual starting dose is 800 milligrams to be followed by 400 milligrams in 6 to 8 hours and 400 milligrams on each of 2 consecutive days. Alternatively your doctor may prescribe a single dose of 800 milligrams.

Lupus Erythematosus

The usual starting dose for adults is 400 milligrams once or twice daily. You will continue to take this dose for several weeks or months depending on your response. For longer-term maintenance therapy your doctor may reduce the dose to 200 to 400 milligrams per day.

Rheumatoid Arthritis

The usual starting dose for adults is 400 to 600 milligrams a day taken with a meal or a glass of milk. If your condition improves usually within 4 to 12 weeks your doctor will reduce the dose to a maintenance level of 200 to 400 milligrams daily.

CHILDREN

For the treatment of malaria your doctor will calculate the dosage on the basis of your child’s weight.

This drug has not been proved safe for treatment of juvenile arthritis.

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Note:

The content in this section is provided for informational purposes only. This information regarding the following Canadian drugs is not intended to replace or act as a substitute for information or advice provided by your physician. You should always consult a physician before beginning a new medication. Moreover, prescription drugs should only be obtained with a doctor's prescription.

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