Prescription Drug Index

SINEMET-CR

This is a Brand Name Prescription Drug

Sinemet-CR

Pronounced: SIN-uh-met see-are

Generic ingredients: Carbidopa Levodopa

Brand Name Drugs

Generic Drugs

Sinemet CR is a controlled-release tablet that may be given to help relieve the muscle stiffness tremor and weakness caused by Parkinson’s disease. It may also be given to relieve Parkinson-like symptoms caused by encephalitis (brain fever) carbon monoxide poisoning or manganese poisoning.

Sinemet CR contains two drugs carbidopa and levodopa. The drug that actually produces the anti-Parkinson’s effect is levodopa. Carbidopa helps to get levodopa into the brain thus allowing levodopa to work more efficiently.

Parkinson’s drugs such as Sinemet CR relieve the symptoms of the disease but are not a permanent cure.

Your doctor will tailor your individual dosage carefully depending on your response to previous therapy and symptoms.

ADULTS

For patients with mild to moderate symptoms the initial recommended dose is 1 tablet of Sinemet CR taken 2 times a day.

Starting doses should be spaced out every 4 to 8 hours and then adjusted to each patient’s individual response.

The usual long-term dose is 2 to 8 tablets per day taken in divided doses every 4 to 8 hours during the waking day.

Higher doses (12 or more tablets per day) and shorter intervals (less than 4 hours) have been used but are not usually recommended.

When doses of Sinemet CR are given at intervals of less than 4 hours and/or if the divided doses are not equal it is recommended that the smaller doses be given at the end of the day.

An interval of at least 3 days between dosage adjustments is recommended.

Dosage adjustment of Sinemet CR may be necessary if your doctor prescribes additional medications.

CHILDREN

Use of Sinemet CR in children under 18 is not recommended.

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Note:

The content in this section is provided for informational purposes only. This information regarding the following Canadian drugs is not intended to replace or act as a substitute for information or advice provided by your physician. You should always consult a physician before beginning a new medication. Moreover, prescription drugs should only be obtained with a doctor's prescription.

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