Prescription Drug Index

Zestoretic is used in the treatment of high blood pressure. It combines an ACE inhibitor drug with a diuretic. Lisinopril the ACE inhibitor works by limiting production of a substance that promotes salt and water retention in your body. Hydrochlorothiazide a diuretic prompts your body to produce and eliminate more urine which helps in lowering blood pressure. Combination products such as Zestoretic are usually not prescribed until therapy is already under way.

ADULTS

Zestoretic is designed to replace higher doses of either component. Dosages of the lisinopril component range from 10 to 80 milligrams a day; dosages of hydrochlorothiazide typically fall between 6.25 and 50 milligrams daily. If either component when prescribed alone fails to control your blood pressure your doctor may try the Zestoretic combination starting with either 10 or 20 milligrams of lisinopril and 12.5 milligrams of hydrochlorothiazide and gradually increasing the dosage as needed.

If you are age 65 or older or have kidney problems your doctor will adjust your dosage with caution. This drug is not prescribed for people with severe kidney damage.

CHILDREN

Safety and effectiveness in children have not been established.

Note:

The content in this section is provided for informational purposes only. This information regarding the following Canadian drugs is not intended to replace or act as a substitute for information or advice provided by your physician. You should always consult a physician before beginning a new medication. Moreover, prescription drugs should only be obtained with a doctor's prescription.

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