Prescription Drug Index

ZESTRIL

This is a Brand Name Prescription Drug

Zestril

Pronounced: ZEST-rill

Generic name: Lisinopril

Brand Name Drugs

Generic Drugs

Lisinopril is used in the treatment of high blood pressure. It is effective when used alone or when combined with other high blood pressure medications. It may also be used with other medications in the treatment of heart failure and may be given within 24 hours of a heart attack to improve chances of survival.

Lisinopril is a type of drug called an ACE inhibitor. It works by reducing production of a substance that increases salt and water retention in your body.

ADULTS

High Blood Pressure

For people not on water pills (diuretics) the initial starting dose is usually 10 milligrams taken 1 time a day. Your doctor will increase the dosage until your blood pressure is under control. The long-term dosage usually ranges from 20 to 40 milligrams a day taken in a single dose.

Diuretic use should if possible be stopped before using lisinopril. If not your physician may give an initial dose of 5 milligrams under supervision before any further medication is prescribed.

People with kidney disorders must be carefully monitored and dosages will be adjusted to the individual’s needs depending on kidney function.

Heart Failure

For this condition lisinopril is usually prescribed along with diuretics and digitalis. The recommended starting dose is 5 milligrams once a day with the first dose taken under your doctor’s supervision. The doctor may increase the dose by up to 10 milligrams at intervals of no less than 2 weeks. Typical long-term dosages range from 5 to 40 milligrams taken once a day.

Heart Attack

The usual dose is 5 milligrams within the first 24 hours after a heart attack then 5 milligrams 24 hours later 10 milligrams 48 hours later and finally 10 milligrams once a day for 6 weeks. If low blood pressure is a problem the doctor may recommend a lower dosage.

CHILDREN

The safety and effectiveness of lisinopril in children have not been established.

OLDER ADULTS

The physician will adjust the dosage carefully according to the individual’s needs.

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Note:

The content in this section is provided for informational purposes only. This information regarding the following Canadian drugs is not intended to replace or act as a substitute for information or advice provided by your physician. You should always consult a physician before beginning a new medication. Moreover, prescription drugs should only be obtained with a doctor's prescription.

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