Prescription Drug Index

CELEBREX

This is a Brand Name Prescription Drug

Celebrex

Pronounced: SELL-eh-breks

Generic name: Celecoxib

Brand Name Drugs

Generic Drugs

Celebrex relieves the pain and inflammation of osteoarthritis and rheumatoid arthritis. It is the first of a new class of nonsteroidal anti-inflammatory drugs (NSAIDs) called COX-2 inhibitors. Like older NSAIDs such as Motrin and Naprosyn Celebrex is believed to fight pain and inflammation by inhibiting the effect of a natural enzyme called COX-2. Unlike the older medications however it does not interfere with a similar substance called COX-1 which exerts a protective effect on the lining of the stomach. Celebrex is therefore less likely to cause the bleeding and ulcers that sometimes accompany sustained use of the older NSAIDs.

Celebrex has also been found to reduce the number of colorectal polyps (growths in the wall of the lower intestine and rectum) in people who suffer from the condition called familial adenomatous polyposis (FAP) an inherited tendency to develop large numbers of colorectal polyps that eventually become cancerous.

ADULTS

Osteoarthritis

The recommended daily dose is 200 milligrams taken as a single dose or in 100-milligram doses twice a day.

Rheumatoid Arthritis

The recommended dose is 100 to 200 milligrams twice a day.

Familial Adenomatous Polyposis

The recommended dose is 400 milligrams twice a day with food.

Dosage is typically cut in half for people with moderate liver problems.

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Note:

The content in this section is provided for informational purposes only. This information regarding the following Canadian drugs is not intended to replace or act as a substitute for information or advice provided by your physician. You should always consult a physician before beginning a new medication. Moreover, prescription drugs should only be obtained with a doctor's prescription.

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