Prescription Drug Index

COMTAN

This is a Brand Name Prescription Drug

Comtan

Pronounced: COM-tan

Generic name: Entacapone

Brand Name Drugs

Generic Drugs

Comtan is used for Parkinson’s disease. It is prescribed when doses of the combination drug levodopa/carbidopa (Sinemet) begin to wear off too soon. By extending the effect of each dose of Sinemet it frees the patient from the stiffness and tremors of Parkinson’s for a longer period of time.

Comtan works by inhibiting the effect of an enzyme that breaks down the levodopa in Sinemet. It has no effect on Parkinson’s disease when used by itself.

ADULTS

The recommended dose is one 200-milligram tablet with each dose of Sinemet up to a maximum of 8 doses per day. If you were taking more than 800 milligrams of levodopa per day before starting Comtan you may need a reduction in your levodopa dose once you begin taking the drug.

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Note:

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