Prescription Drug Index

EPIVAL

This is a Brand Name Prescription Drug

Epival

Pronounced: Epp-eh-val

Generic name: Divalproex sodium

Brand Name Drugs

Generic Drugs

Divalproex is converted to valproic acid in your body however Divalproex is easier on the stomach than valproic acid and this may be one of the reasons that your doctor has chosen this medication.

Epival in both delayed-release tablet and capsule form is used to treat certain types of seizures and convulsions. It may be prescribed alone or with other epilepsy medications.

The delayed-release tablets are also used to control the manic episodes--periods of abnormally high spirits and energy--that occur in bipolar disorder (manic depression).

An extended-release form of this drug Depakote ER is prescribed to prevent migraine headaches. The delayed-release tablets are also used for this purpose.

EPILEPSY

Dosage for adults and children 10 years of age or older is determined by body weight. The usual recommended starting dose is 10 to 15 milligrams per 2.2 pounds per day depending on the type of seizure. Your doctor may increase the dose at 1-week intervals by 5 to 10 milligrams per 2.2 pounds per day until your seizures are controlled or the side effects become too severe. The most you should take is 60 milligrams per 2.2 pounds per day. If your total dosage is more than 250 milligrams a day your doctor will divide it into smaller individual doses.

Older adults usually begin taking this medication at lower dosages and the dosage is increased more slowly.

MANIC EPISODES

The usual starting dose for those aged 18 and over is 750 milligrams a day divided into smaller doses. Your doctor will adjust the dose for best results.

MIGRAINE PREVENTION

Delayed-Release Tablets

The usual starting dose for those aged 16 and over is 250 milligrams twice a day. Your doctor will adjust the dose up to a maximum of 1000 milligrams a day.

Extended-Release Tablets

The usual starting dose is 500 milligrams once a day for 1 week. The dose may then be increased to 1000 milligrams once a day.

Depakote delayed-release and extended-release tablets work differently so you cannot substitute one type for the other.

Researchers have not established the safety and effectiveness of Epival for prevention of migraines in children or adults over 65.

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Note:

The content in this section is provided for informational purposes only. This information regarding the following Canadian drugs is not intended to replace or act as a substitute for information or advice provided by your physician. You should always consult a physician before beginning a new medication. Moreover, prescription drugs should only be obtained with a doctor's prescription.

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